Yu Lab - Brigham and women's Hospital


BMP and TGF-beta signaling

Signal transduction in embryogenesis and tissue remodeling

Chemical Biology

Small molecule probes of BMP and TGF-beta signaling

Cardiopulmonary Physiology

Mechanisms of pulmonary arterial hypertension

Molecular imaging of pulmonary vascular disease

Translational applications

Recent Publications

BMP6 and oxidized LDL recruit osteogenic differentiation in endothelial cells

Lai-Ming Yung et al. Cardiovascular Research 2015

BMP and TGF-beta signaling in Cardiovascular Disease

Nicholas W. Morrell et al. Nature Cardiology Reviews 2016

Activin A mediates fibrodysplasia ossificans progressiva

Sarah J. Hatsell et al. Science Translational Medicine 2015

Selective enhancement of endothelial BMPR-II with BMP9 reverses pulmonary arterial hypertension.

Lu Long et al. Nature Medicine 2015

Get in touch